According to the publication in Nature (https://www.nature.com/articles/s41591-020-0820-9), the spike protein of SARS-CoV-2 has a polybasic cleavage site due to an insertion of 12 nucleotides at the region encoding the junction of S1 and S2 subunits. "This allows effective cleavage by furin and other...
The newly added feature that allows instant BLASTN comparison of aligned sequences can be applied to an interactive sequence comparison for multiple accessions of the infamous coronavirus COVID-19. We also added bat RaTG13 and bat-SL-CoVZC45 coronaviruses and an older SARS-CoV to the...
We are introducing a new feature that allows to compare nucleotides of aligned maps with one click. First, open two maps to be compared. The lines that connect common markers or homologous genes will help you locate syntenic regions. Zoom...
We rolled out a new version of Web Persephone with major feature upgrade: the users can upload their own tracks, and we made sure that all possible optimizations necessary to achieve maximum performance are in place. The system should handle...
This week's addition is a pair of citrus genomes: C.sinensis (sweet orange) and (pomelo). We uploaded the genomic sequences with annotation tracks to the Desktop and Web versions. As usual, a routine alignment of syntenic chromosomes reveals large structural rearrangements. We...
In addition to an older Wm82.a2.v1, we have now the version Wm82.a4.v1 of the soybean genome. We added the new data set to the Desktop and to the Web versions. Connecting similar genes helps visualizing the changes between the two...
We have downloaded the assembly and annotation of the reference tomato genome version SL4.0, as well as other tomato varieties such as M82 or FLA.8924. The data is coming from http://solgenomics.net. For now, the new map set has the following tracks: ...
We expanded our repository of public genomes by adding one more genome assembly with annotation: corn cultivar Mo17. Aligning it with AGPv4 B73 maps reveals structural variations between the two cultivars.Please follow this link to see this example in the...
ClinVar is a freely accessible, public archive of reports of the relationships among human variations and phenotypes, with supporting evidence. We have created a track with 441,959 markers corresponding to the ClinVar entries. Each marker has multiple qualifiers including the ones that...
We have replaced an older Lucene search engine with a more advanced Apache Solr. We are very pleased with the results of the change: besides much improved response times for fetching the results, the indexing process is now 5 times faster. The search...