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Feature Update: Automatic Coverage Track Generated For VCF Files

21:45 18 November 2025 in General News, Software Updates, Web Version

The data for variants loaded from a VCF file can contain sequencing coverage depth (the DP tag in the INFO field). We now allow the automated creation of a quantitative track that stores these DP values. This feature will work with the user files imported through the main Persephone client application as well as with the files loaded to the database using PersephoneShell command line processor.

If you have a gVCF file, the coverage track will be created for all consecutive bases. The variant data can be filtered to exclude sites that have no alternative alleles. This will significantly reduce the data size for the variant track while preserving all the details for the coverage histogram.