The new version Wm82.a6.v1 of the soybean genome has been loaded to Persephone. The sequence has sometimes-substantial differences from the previous version (Wm82.a4.v1). The analysis of the new assembly by Mary Jane C. Espina et.al. has been published here. Our collection...
We're excited to share that CoverCress Inc. has licensed Persephone, our advanced genome visualization platform! This collaboration marks a significant step forward in the development of the CoverCress crop (domesticated pennycress). CoverCress Inc. (CCI) is leading the way in transforming pennycress into a sustainable, high-value oilseed using...
SAM flags are part of the Sequence Alignment Map (SAM) file format. These flags are bitwise values that describe various properties of a read in a SAM file, such as whether it is paired, mapped, reversed, or a duplicate. The...
Persephone uses tables in multiple parts of the interface. We have added extra context menus to most of them, providing control over the way the data is displayed. For example, users can now edit columns by selecting checkboxes in the...
At a certain level of zoom, when it is possible to distinguish individual bases, we provide an option to display the translation of the genomic sequence in 3 frames. Showing the opposite strand can also add three more translation frames....
We significantly increased the limits on the amount of data displayed in BAM/CRAM tracks. There can be genomic regions with a large number of mapped reads. Persephone can now handle peaks of up to 300,000 reads. Naturally, they all will...
To enhance the visibility of protein-coding segments (CDS) in gene model glyphs, we are now displaying introns within the CDS differently from those in the untranslated regions. This improvement will aid in visualizing human genes that are known for their...
The Cannabis pangenome from the Michael Lab at the Salk Institute is now available in Persephone. With previously loaded genomes from NCBI and CSGDB, our collection has 97 assemblies with gene annotation. We also calculated orthologous gene pairs, which allow...
The Persephone version, published recently, presents a few improvements. Drag-and-drop VCF files. Users are now able to import their VCF files. The remote files are referenced by a URL, and the local files can be added via drag-and-drop. For files larger than...
Genetic variations impact gene translation beyond simple amino acid substitutions. A single nucleotide change or indel can disrupt a splice site, altering the final polypeptide product of a gene. Our "Translation Changes" interface highlights variants that lead to modified protein...