Persephone is available as a web application at https://web.persephonesoft.com
It is fully functional and free to use. Our portal hosts many popular genomes (about 350 genomes total). Please let us know if you don’t find your favorite organism.
You can add your data, which will be seamlessly integrated with the data from our system. Please note that your datasets will be visible to you only. Users who want to add the data must register with an email address. We give each user 5 GB of disk space by default. The large bam/cram files can be addressed remotely by a URL without loading into the system. This way, only the small index file will be transferred and stored on disk, not taking too much of the disk quota.
The full list of features of Persephone is available here.
It might be that the functionality of our portal is enough for you to perform your research. If so, please keep using it and give us your feedback.
At the same time, you will need the license if you decide to host Persephone on your hardware and serve your proprietary data inside your organization. Your personal installation will allow you to use the power of the loading tool PersephoneShell. The command-line application can run multiple tasks that analyze and load the data. Besides straightforward functions, such as loading genomic sequences or annotation, there are commands that create marker tracks by cutting small sequence tags from a given genome and mapping them onto other genomes. Such tracks are automatically linked by common markers and help align the maps. Another way of aligning the maps is based on orthologous gene pairs, which can be easily calculated by running another command of PersephoneShell. Other advantages of running your personal instance include adding custom hyperlinks to different object properties, thus providing ways of integrating Persephone with other resources.
Please let us know if you decide to host Persephone “in-house”.
